hrp0089p1-p094 | Fat, Metabolism and Obesity P1 | ESPE2018

Association of Single Nucleotide Polymorphisms in TNFA, PNPLA3, ADIPOQ and APOC3 Genes with Obesity and Non-Alcoholic Fatty Liver Disease in North Indian Adolescents

Jain Vandana , Kumar Anil , Jana Manisha , Kalaivani Mani

Background: Polymorphisms in several genes may be associated with a higher risk of obesity and non-alcoholic fatty liver disease (NAFLD).Objective: To examine the association of single nucleotide polymorphisms (SNPs) −238G>A, −1031 T>C and −863 C>A of Tumor Necrosis Factor-α (TNFA) gene; rs738409 C>G of patatin-like phospholipase domain containing 3 (PNPLA3) gene; +276 G>T and +45 T>G of Ad...